PhD student positions in molecular parasitology

3 PhD student positions in molecular parasitology available at the Life Science Research Centre, University of Ostrava, Ostrava Czech Republic from September 1st, 2017 in the laboratory of Molecular protozoology (Dr. Vyacheslav Yurchenko, http://www1.osu.cz/~yurchenko/)

1. To study the limits of trypanosomatids’ biodiversity using molecular phylogenetic and phylogenomic methods.
Requirements: fluent English, knowledge of molecular phylogenetic principles and approaches. Basic bio-computing (e.g. genome and transcriptome analysis) and statistics experience are advantageous.
Recent publications:
Kostygov, A., Dobáková, E., Grybchuk-Ieremenko, A., Váhala, D., Maslov, D., Votýpka, J., Lukeš, J., Yurchenko, V. Novel trypanosomatid –bacterium association: evolution of endosymbiosis in action. mBio, 2016, 7(2): e01985-15. PMID: 26980834.
Votýpka, J., d’Avila-Levy, C., Grellier, P., Maslov, D., Lukeš, J., Yurchenko, V. New approaches to systematics of Trypanosomatidae: criteria for taxonomic (re)description. Trends Parasitol., 2015, 31: 460-469. PMID: 26433249.

2. To study the molecular mechanisms governing translation in Blastocrithidia sp.
Requirement: fluent English, advanced molecular biology skills (DNA, RNA, protein analyses, genome manipulations). Basic bio-computing experience (e.g. genome and transcriptome analysis) is advantageous.
Recent publication:
Záhonová, K., Kostygov, A., Ševčíková, T., Yurchenko, V., Eliáš, M. An unprecedented non-canonical nuclear genetic code with all three termination codons reassigned as sense codons. Curr. Biol., 2016, 26(17): 2364-2369. PMID: 27593378.

3. To study novel virulence factors in Leishmania infection
Requirements: fluent English, advanced molecular biology skills (DNA, RNA, protein analyses, genome manipulations). Basic bio-computing experience (e.g. genome and transcriptome analysis) is advantageous.
Recent publications:
Flegontov, P., Butenko, A., Firsov. S., Kraeva, N., Eliáš, M., Field, M., Filatov, D., Flegontova, O., Gerasimov, E., Hlaváčová, J., Ishemgulova, A., Jackson, A., Kelly, S., Kostygov. A., Logacheva, M., Maslov, D., Opperdoes, F., O’Reilly, A., Sádlová, J., Ševčíková, T., Venkatesh, D., Vlček, Č., Volf, P., Votýpka, J., Záhonová, K., Yurchenko, V., Lukeš, J. Genome of Leptomonas pyrrhocoris: a high-quality reference for monoxenous trypanosomatids and new insights into evolution of Leishmania. Sci. Rep., 2016, 6: 23704. PMID: 27021793.
Kraeva, N., Butenko, A., Hlaváčová, J., Kostygov, A., Myškova, J., Grybchuk, D., Leštinová, T., Votýpka, J., Volf, P., Opperdoes, F., Flegontov, P., Lukeš, J., Yurchenko, V. Leptomonas seymouri: adaptations to the dixenous life cycle analyzed by genome sequencing, transcriptome profiling and co-infection with Leishmania donovani. PLOS Path., 2015, 11(8): e1005127. PMID: 226317207.
Kraeva, N., Ishemgulova, A, Lukeš, J., Yurchenko, V. Tetracycline-inducible gene expression system in Leishmania mexicana. Mol. Biochem. Parasitol., 2014, 198: 11-13. PMID: 25461484.