Île-de-France, France
Date Posted
5 Dec 2024

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PhD Program
Institut Curie

PhD Program – 12 PhD positions in October 2018 at Institut Curie (COFUND)

Île-de-France, France
5 Dec 2024

NOTE: this position listing has expired and may no longer be relevant!

Position Description

Institut Curie is recruiting 12 PhD students through its international program called IC-3i PhD Program. This program, part funded by the European Commission’s MSCA COFUND scheme, provides PhD students with a 3-year doctoral contract, a high level interdisciplinary, inter-sectorial, and international training with dedicated career development plans, secondments and mentoring.

PhD research projects in life sciences cover Institut Curie’s main research domains:
✓ Biology & Chemistry of Radiations, Cell Signaling & Cancer
✓ Development, Cancer, Genetics & Epigenetics
✓ Integrative Tumour Biology, Immunology & Environment
✓ Multiscale Physics-Biology-Chemistry & Cancer

Institut Curie brings together a world-class multidisciplinary cancer research center and a model hospital group in Paris and surroundings. By embracing cross-disciplinary approaches, it drives the discovery of more effective treatments and leads to improved patient care.

Open positions

✓ Biology & Chemistry of Radiations, Cell Signaling & Cancer
• Development of indirect inhibitors of O6-methyguanine-DNA-methyltransferase (MGMT) for combination chemotherapy of temozolomide-resistant gliomas
Anton GRANZHAN / Sophie BOMBARD research group: Molecular recognition of nucleic acids

• Multi-scale imaging and study of the perivascular niche in glioblastoma
Giorgio SEANO research group: Normal & pathological signaling: from the embryo to the innovative therapy of cancers

✓ Development, Cancer, Genetics & Epigenetics
• Imaging transcription in living embryos to decipher the robustness of patterning
Nathalie DOSTATNI research group: Epigenetic plasticity and polarity of the embryo

• Defining cell fate specification of mouse mammary stem cells in 4D
Silvia FRE / Lloyd-Lewis BETHAN research group: Notch Signaling in Stem Cells and Tumors

• lncRNA-directed neural stem cell regulation in the developing and aging brain
Alena SHKUMATAVA research group: LincRNAs in Vertebrate Development

• Modeling the dynamics and heterogeneity of epigenetic and transcriptomic states during treatment and acquisition of resistance in breast cancer
Céline VALLOT research group: Dynamics of epigenetic plasticity in cancer

✓ Integrative Tumour Biology, Immunology & Environment
• Replication fork stability and resistance to PARP inhibitors in homologous recombination (HR)-deficient tumors
Raphael CECCALDI research group: Alternative DNA Repair in Cancer

• Identifying novel molecular regulators of human monocyte differentiation
Elodie SEGURA research group: Antigen Presentation in Dendritic Cells

✓ Multiscale Physics-Biology-Chemistry & Cancer
• Cause-effect analyses of breast cancer clinical records from Institut Curie
Hervé ISAMBERT / Fabien REYAL research group: Evolution of Biomolecular Networks, RNA Dynamics

• Deciphering how centrosome dysfunctions lead to microcephaly
Véronique MARTHIENS / Renata BASTO research group: Biology of Centrosomes and Cilia

• Synchronizing Transport from the Plasma Membrane to the Endoplasmic Reticulum: New assays, new questions, new applications
Franck PEREZ research group: Dynamics of Intra-Cellular Organization

• Role of altered lysosome positioning in bladder cancer progression
Kristine SCHAUER research group: Molecular Mechanisms of Intracellular Transport

(More details on Institut Curie’s IC-3i International PhD Program webpage)

How to Apply

• Eligibility criteria Applicants: - must not have lived or worked in France for more than 12 months during the past 3 years prior to January 18th 2018, - must have a Master’s degree (or be about to obtain one) or have a university degree equivalent to a European Master’s degree (5-year duration), - must have obtained this degree no more than 2 years ago. • Application and selection process Application deadline: January 18th, 2018 at 5:00pm (CET) Candidates have to complete an online form in English in time via the web-based application portal. Applications will be evaluated through a three steps process: 1) Eligibility check of applications in February 2018. 2) 1st round selection: Evaluation of applications by Review Board in March 2018. Results in April 2018. 3) 2nd round selection: Shortlisted candidates during 1st round selection will be invited for an interview session in Paris from May 16 to May 18, 2018. Final results will be given at the beginning of June 2018. • Additional information - The IC-3i PhD Program is in English. - International applicants willing to apply for the IC-3i PhD Program should inquire about the visa procedure regarding their country, in preparation for step 3 (interview session in Paris). This project has received funding from the European Union’s Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie grant agreement No 666003.

Position Category: Medical & Biological Sciences. Position Type: PhD Program. Position Tags: genetics, physics, chemistry, biology, immunology, research, cancer, and translational.