Date Posted
1 Jan 2024

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PhD Project

PhD position in evolutionary genetics

1 Jan 2024

NOTE: this position listing has expired and may no longer be relevant!

Position Description

Our aim is to exploring the evolutionary conserved genetic aspects of bone-muscle ‎interactions in vertebrates, by in-vitro and in-vivo experiments. In particular, we aim to ‎produce gene targets for pharmacological treatment for human disease, as well as for ‎aquaculture. ‎
In particular, the candidate will: ‎
‎- detect effects of the genes newly identified by association study on the musculoskeletal ‎system by tracing expression levels in bone and muscle cells in Zebrafish (Danio rerio)‎
‎- estimate effects of silencing and knocking-out potentially pleiotropic genes in Zebrafish and ‎medaka, by generation of CRISPR/Cas9 mutant fish.‎
Candidates with M.Sc. in the following research areas should apply: Molecular biology, ‎Developmental biology, Medical Neurobiology, Microbiology, Molecular Genetics, ‎Immunology, and Endocrinology. An experience of working with small fish is a plus as the ‎student will be involved with the maintenance of zebrafish strains, breeding and embryonic ‎manipulations. The position requires an experience in general molecular biology protocols. ‎Characterization of muscle and bone phenotypes is performed by advanced imaging ‎techniques (microCT, fluorescent microscopy etc.) The research is performed in ‎collaboration with the EU and US-based colleagues; there is a possibility of training in ‎Singapore.‎

How to Apply

The position is at the Azrieli Faculty of Medicine of BIU in Safed, in the Galilee region of ‎Israel. . For additional information please ‎send your CV and introduction letter to Prof. David Karasik ( and to ‎Dr. Chen Shochat ( ). ‎

Position Category: Medical & Biological Sciences. Position Type: PhD Project. Position Tags: fish, genome, human, skeletal, and crispr. Salary: €10'000 - €20'000.