Date Posted
13 Jun 2024

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PhD Project
University of Italian Switzerland

PhD position in Computational Biology

13 Jun 2024

NOTE: this position listing has expired and may no longer be relevant!

Position Description

A PhD position is available in the Limongelli Research Group at USI Lugano (Switzerland). The summary below is a broad overview of our research activity and the skills that the candidate should have.

Topics: Our research group uses standard and advanced computational methods to study the ligands interaction with their biological targets and the complex functional mechanisms of biomolecules (e.g. proteins and nucleic acids). We use standard techniques like Molecular Docking and Molecular Dynamics as well as more advanced methods like Umbrella Sampling, Steered Dynamics, Metadynamics. Particular focus is dedicated to the development and application of innovative computational protocols aimed at studying long time scale processes (> microsecond) in large systems (e.g. membrane proteins). We aim to create theoretical models that represent the complex behavior of bio-systems into a much simpler set of underlying chemico-physical concepts.

Candidate: The applicant must have basic knowledge of the UNIX operating system and of computational chemistry/biology. He/she will be involved in the study of ligand/protein and protein/protein binding using both atomistic and coarse-grained simulations. Skills in physics and informatics are also welcome. Ability to work independently as well as to collaborate with a team is certainly a premium.
Due to the key role that this student will cover in the group, the selection will be highly competitive and the salary above the European standards.
Some publications are available at:

More information on my website:

How to Apply

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Position Category: Medical & Biological Sciences. Position Type: PhD Project.