PhD Program – 12 PhD positions in October 2018 at Institut Curie (COFUND)

Institut Curie is recruiting 12 PhD students through its international program called IC-3i PhD Program. This program, part funded by the European Commission’s MSCA COFUND scheme, provides PhD students with a 3-year doctoral contract, a high level interdisciplinary, inter-sectorial, and international training with dedicated career development plans, secondments and mentoring.

PhD research projects in life sciences cover Institut Curie’s main research domains:
✓ Biology & Chemistry of Radiations, Cell Signaling & Cancer
✓ Development, Cancer, Genetics & Epigenetics
✓ Integrative Tumour Biology, Immunology & Environment
✓ Multiscale Physics-Biology-Chemistry & Cancer

Institut Curie brings together a world-class multidisciplinary cancer research center and a model hospital group in Paris and surroundings. By embracing cross-disciplinary approaches, it drives the discovery of more effective treatments and leads to improved patient care.

Open positions

✓ Biology & Chemistry of Radiations, Cell Signaling & Cancer
• Development of indirect inhibitors of O6-methyguanine-DNA-methyltransferase (MGMT) for combination chemotherapy of temozolomide-resistant gliomas
Anton GRANZHAN / Sophie BOMBARD research group: Molecular recognition of nucleic acids

• Multi-scale imaging and study of the perivascular niche in glioblastoma
Giorgio SEANO research group: Normal & pathological signaling: from the embryo to the innovative therapy of cancers

✓ Development, Cancer, Genetics & Epigenetics
• Imaging transcription in living embryos to decipher the robustness of patterning
Nathalie DOSTATNI research group: Epigenetic plasticity and polarity of the embryo

• Defining cell fate specification of mouse mammary stem cells in 4D
Silvia FRE / Lloyd-Lewis BETHAN research group: Notch Signaling in Stem Cells and Tumors

• lncRNA-directed neural stem cell regulation in the developing and aging brain
Alena SHKUMATAVA research group: LincRNAs in Vertebrate Development

• Modeling the dynamics and heterogeneity of epigenetic and transcriptomic states during treatment and acquisition of resistance in breast cancer
Céline VALLOT research group: Dynamics of epigenetic plasticity in cancer

✓ Integrative Tumour Biology, Immunology & Environment
• Replication fork stability and resistance to PARP inhibitors in homologous recombination (HR)-deficient tumors
Raphael CECCALDI research group: Alternative DNA Repair in Cancer

• Identifying novel molecular regulators of human monocyte differentiation
Elodie SEGURA research group: Antigen Presentation in Dendritic Cells

✓ Multiscale Physics-Biology-Chemistry & Cancer
• Cause-effect analyses of breast cancer clinical records from Institut Curie
Hervé ISAMBERT / Fabien REYAL research group: Evolution of Biomolecular Networks, RNA Dynamics

• Deciphering how centrosome dysfunctions lead to microcephaly
Véronique MARTHIENS / Renata BASTO research group: Biology of Centrosomes and Cilia

• Synchronizing Transport from the Plasma Membrane to the Endoplasmic Reticulum: New assays, new questions, new applications
Franck PEREZ research group: Dynamics of Intra-Cellular Organization

• Role of altered lysosome positioning in bladder cancer progression
Kristine SCHAUER research group: Molecular Mechanisms of Intracellular Transport

(More details on Institut Curie’s IC-3i International PhD Program webpage)