A PhD position

A Ph.D. student position is available in the laboratory of a leading researcher at the Weizmann Institute in Israel studying signaling for activation of transcription factors of the NF-kappa B family.

Biological questions and assays are focused on signaling mechanisms that are activated by receptors of the TNF family and on the regulation of gene activation by them.

The fellow will apply state-of-the-art molecular and genomic tools to pursue projects along the following lines:

Molecular dissection of the signaling events, identification of their key regulatory proteins, regulatory RNAs and genomic structures by genetic and proteomic approaches.
Functional evaluation on animal models by conditional targeted disruption of genes and BAC transgenesis.

The successful candidates will be skilled in all aspects of molecular and cell biology, with thorough theoretical background and strong desire to understand basic science and to perform mechanistic studies. Extensive first-hand experience in molecular and cell biology is crucial. Experience with mouse models will be beneficial. Fair English, both spoken and written, excellent communication skills, ability to apply new techniques and perform independently, as well as a part of a multi-national team, are essential.

Interested applicants should mail their curriculum vitae, their expertise, short statement of intent and names and addresses of three references to Rachel.Valdman@weizmann.ac.il